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Kinetic Proofreading of Ligand-FcεRI Interactions May Persist beyond LAT Phosphorylation

Cells may discriminate among ligands with different dwell times for receptor binding through a mechanism called kinetic proofreading in which the formation of an activated receptor complex requires a progression of events that is aborted if the ligand dissociates before completion. This mechanism ex...

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Détails bibliographiques
Auteurs principaux: Torigoe, Chikako, Faeder, James R., Oliver, Janet M., Goldstein, Byron
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593628/
https://ncbi.nlm.nih.gov/pubmed/17339448
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