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A Mechanistic Model of Early FcεRI Signaling: Lipid Rafts and the Question of Protection from Dephosphorylation

We present a model of the early events in mast cell signaling mediated by FcεRI where the plasma membrane is composed of many small ordered lipid domains (rafts), surrounded by a non-order region of lipids consisting of the remaining plasma membrane. The model treats the rafts as transient structure...

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Detalhes bibliográficos
Main Authors: Barua, Dipak, Goldstein, Byron
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524258/
https://ncbi.nlm.nih.gov/pubmed/23284735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051669
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