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Kinetic Proofreading of Ligand-FcεRI Interactions May Persist beyond LAT Phosphorylation
Cells may discriminate among ligands with different dwell times for receptor binding through a mechanism called kinetic proofreading in which the formation of an activated receptor complex requires a progression of events that is aborted if the ligand dissociates before completion. This mechanism ex...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593628/ https://ncbi.nlm.nih.gov/pubmed/17339448 |
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