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PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics
The pregnane X receptor (PXR; NR1I2), a member of the nuclear receptor superfamily, regulates the expression of drug-metabolic enzymes and transporters involved in the responses of mammals to their chemical environment. The same enzyme and transporter systems are also involved in the homeostasis of...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593625/ https://ncbi.nlm.nih.gov/pubmed/19018724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/14622416.9.11.1695 |
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