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Isoform-selective histone deacetylase inhibitors

Histone deacetylase (HDAC) proteins are transcription regulators linked to cancer. As a result, multiple small molecule HDAC inhibitors are in various phases of clinical trials as anti-cancer drugs. The majority of HDAC inhibitors non-selectively influence the activities of eleven human HDAC isoform...

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Podrobná bibliografie
Hlavní autoři: Bieliauskas, Anton V., Pflum, Mary Kay H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593472/
https://ncbi.nlm.nih.gov/pubmed/18568166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b703830p
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