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Anchorage-Independent Growth of Pocket Protein-Deficient Murine Fibroblasts Requires Bypass of G(2) Arrest and Can Be Accomplished by Expression of TBX2

Mouse embryonic fibroblasts (MEFs) deficient for pocket proteins (i.e., pRB/p107-, pRB/p130-, or pRB/p107/p130-deficient MEFs) have lost proper G(1) control and are refractory to Ras(V12)-induced senescence. However, pocket protein-deficient MEFs expressing Ras(V12) were unable to exhibit anchorage-...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Vormer, Tinke L., Foijer, Floris, Wielders, Camiel L. C., te Riele, Hein
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology (ASM) 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593436/
https://ncbi.nlm.nih.gov/pubmed/18936168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00313-08
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