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PML Activates Transcription by Protecting HIPK2 and p300 from SCF(Fbx3)-Mediated Degradation

PML, a nuclear protein, interacts with several transcription factors and their coactivators, such as HIPK2 and p300, resulting in the activation of transcription. Although PML is thought to achieve transcription activation by stabilizing the transcription factor complex, little is known about the un...

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Библиографические подробности
Главные авторы: Shima, Yutaka, Shima, Takito, Chiba, Tomoki, Irimura, Tatsuro, Pandolfi, Pier Paolo, Kitabayashi, Issay
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593379/
https://ncbi.nlm.nih.gov/pubmed/18809579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00897-08
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