ロード中...

Genotoxic Stress-Induced Cyclin D1 Phosphorylation and Proteolysis Are Required for Genomic Stability

While mitogenic induction of cyclin D1 contributes to cell cycle progression, ubiquitin-mediated proteolysis buffers this accumulation and prevents aberrant proliferation. Because the failure to degrade cyclin D1 during S-phase triggers DNA rereplication, we have investigated cellular regulation of...

詳細記述

保存先:
書誌詳細
主要な著者: Pontano, Laura L., Aggarwal, Priya, Barbash, Olena, Brown, Eric J., Bassing, Craig H., Diehl, J. Alan
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593367/
https://ncbi.nlm.nih.gov/pubmed/18809569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01085-08
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!