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Stem-Loop Silencing Reveals that a Third Mitochondrial DNA Polymerase, POLID, Is Required for Kinetoplast DNA Replication in Trypanosomes

Kinetoplast DNA (kDNA), the mitochondrial genome of trypanosomes, is a catenated network containing thousands of minicircles and tens of maxicircles. The topological complexity dictates some unusual features including a topoisomerase-mediated release-and-reattachment mechanism for minicircle replica...

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Bibliografiske detaljer
Main Authors: Chandler, Julian, Vandoros, Anthula V., Mozeleski, Brian, Klingbeil, Michele M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593185/
https://ncbi.nlm.nih.gov/pubmed/18849470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00199-08
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