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Three Mitochondrial DNA Polymerases Are Essential for Kinetoplast DNA Replication and Survival of Bloodstream Form Trypanosoma brucei

Trypanosoma brucei, the causative agent of human African trypanosomiasis, has a complex life cycle that includes multiple life cycle stages and metabolic changes as the parasite switches between insect vector and mammalian host. The parasite's single mitochondrion contains a unique catenated mi...

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Bibliographic Details
Main Authors: Bruhn, David F., Sammartino, Mark P., Klingbeil, Michele M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127672/
https://ncbi.nlm.nih.gov/pubmed/21531873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.05008-11
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