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Trypanosomes Have Six Mitochondrial DNA Helicases, with One Controlling Kinetoplast Maxicircle Replication
Kinetoplast DNA (kDNA), the trypanosome mitochondrial DNA, contains thousands of minicircles and dozens of maxicircles interlocked in a giant network. Remarkably, Trypanosoma brucei's genome encodes eight PIF1-like helicases, six of which are mitochondrial. We now show that TbPIF2 is essential...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2763077/ https://ncbi.nlm.nih.gov/pubmed/19646907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.07.004 |
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