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TbPIF1, a Trypanosoma brucei Mitochondrial DNA Helicase, Is Essential for Kinetoplast Minicircle Replication

Kinetoplast DNA, the trypanosome mitochondrial genome, is a network of interlocked DNA rings including several thousand minicircles and a few dozen maxicircles. Minicircles replicate after release from the network, and their progeny reattach. Remarkably, trypanosomes have six mitochondrial DNA helic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Beiyu, Yildirir, Gokben, Wang, Jianyang, Tolun, Gökhan, Griffith, Jack D., Englund, Paul T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844155/
https://ncbi.nlm.nih.gov/pubmed/20042610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.084038
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