Trypanosoma brucei Orc1 Is Essential for Nuclear DNA Replication and Affects Both VSG Silencing and Switching

Binding of the Origin Recognition Complex (ORC) to replication origins is essential for initiation of DNA replication, but ORC has non-essential functions outside of DNA replication, including in heterochromatic gene silencing and telomere maintenance. Trypanosoma brucei, a protozoan parasite that c...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Benmerzouga, Imaan, Concepción-Acevedo, Jeniffer, Kim, Hee-Sook, Vandoros, Anthula V., Cross, George A.M., Klingbeil, Michele M., Li, Bibo
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535549/
https://ncbi.nlm.nih.gov/pubmed/23216794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12093
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares