Suppression of subtelomeric VSG switching by Trypanosoma brucei TRF requires its TTAGGG repeat-binding activity

Trypanosoma brucei causes human African trypanosomiasis and regularly switches its major surface antigen, VSG, in the bloodstream of its mammalian host to evade the host immune response. VSGs are expressed exclusively from subtelomeric loci, and we have previously shown that telomere proteins TbTIF2...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Jehi, Sanaa E., Li, Xiaohua, Sandhu, Ranjodh, Ye, Fei, Benmerzouga, Imaan, Zhang, Mingjie, Zhao, Yanxiang, Li, Bibo
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Structural Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227783/
https://ncbi.nlm.nih.gov/pubmed/25313155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku942
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