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Trypanosoma brucei TIF2 and TRF Suppress VSG Switching Using Overlapping and Independent Mechanisms

Trypanosoma brucei causes debilitating human African trypanosomiasis and evades the host’s immune response by regularly switching its major surface antigen, VSG, which is expressed exclusively from subtelomeric loci. We previously showed that two interacting telomere proteins, TbTRF and TbTIF2, are...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jehi, Sanaa E., Nanavaty, Vishal, Li, Bibo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892550/
https://ncbi.nlm.nih.gov/pubmed/27258069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156746
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