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Viral and host factors induce macrophage activation and loss of Toll Like Receptor tolerance in chronic HCV infection
BACKGROUND&AIMS: Persistent inflammation contributes to progression of liver damage in chronic HCV (cHCV) infection. Repeated exposure to Toll like receptor (TLR) ligands results in tolerance, a protective mechanism aimed at limiting inflammation. METHODS: Monocytes/macrophages were repeatedly s...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593079/ https://ncbi.nlm.nih.gov/pubmed/17916356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2007.08.003 |
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