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The Opposite Effects of Acute and Chronic Alcohol on Lipopolysaccharide-Induced Inflammation Are Linked to IRAK-M in Human Monocytes()

Impaired host defense after alcohol use is linked to altered cytokine production, however, acute and chronic alcohol differently modulate monocyte/macrophage activation. We hypothesized that in human monocytes, acute alcohol induces hyporesponsiveness to LPS, resulting in decreased TNF-α, whereas ch...

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Detalhes bibliográficos
Main Authors: Mandrekar, Pranoti, Bala, Shashi, Catalano, Donna, Kodys, Karen, Szabo, Gyongyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845821/
https://ncbi.nlm.nih.gov/pubmed/19561104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803206
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