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In Vitro and In Vivo Validation of ligA and tarI as Essential Targets in Staphylococcus aureus

A conditional expression system has been developed using the isopropyl-β-d-thiogalactopyranoside (IPTG)-inducible Pspac promoter to validate essential genes of Staphylococcus aureus in vivo. The system has been applied to prove the essentiality of ligA and to evaluate the function of tarI, which was...

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Hlavní autoři: Streker, Karin, Schäfer, Tina, Freiberg, Christoph, Brötz-Oesterhelt, Heike, Hacker, Jörg, Labischinski, Harald, Ohlsen, Knut
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592864/
https://ncbi.nlm.nih.gov/pubmed/18809938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00548-07
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