In Vitro and In Vivo Validation of ligA and tarI as Essential Targets in Staphylococcus aureus

A conditional expression system has been developed using the isopropyl-β-d-thiogalactopyranoside (IPTG)-inducible Pspac promoter to validate essential genes of Staphylococcus aureus in vivo. The system has been applied to prove the essentiality of ligA and to evaluate the function of tarI, which was...

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Detaylı Bibliyografya
Asıl Yazarlar: Streker, Karin, Schäfer, Tina, Freiberg, Christoph, Brötz-Oesterhelt, Heike, Hacker, Jörg, Labischinski, Harald, Ohlsen, Knut
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Analytical Procedures
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592864/
https://ncbi.nlm.nih.gov/pubmed/18809938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00548-07
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