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Immunoprotective properties of recombinant LigA and LigB in a hamster model of acute leptospirosis

Leptospirosis is the most widespread zoonosis and is considered a major public health problem worldwide. Currently, there is no widely available vaccine against leptospirosis for use in humans. A purified, recombinant subunit vaccine that includes the last six immunoglobulin-like (Ig-like) domains o...

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Publicado en:PLoS One
Main Authors: Evangelista, Karen V., Lourdault, Kristel, Matsunaga, James, Haake, David A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509140/
https://ncbi.nlm.nih.gov/pubmed/28704385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180004
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