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Smoothened Signaling in Vertebrates Is Facilitated by a G Protein-coupled Receptor Kinase
Smoothened, a heptahelical membrane protein, functions as the transducer of Hedgehog signaling. The kinases that modulate Smoothened have been thoroughly analyzed in flies. However, little is known about how phosphorylation affects Smoothened in vertebrates, mainly, because the residues, where Smoot...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The American Society for Cell Biology
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2592680/ https://ncbi.nlm.nih.gov/pubmed/18815277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-05-0448 |
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