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Phenotypic Regulation of the Sphingosine 1-Phosphate Receptor Miles Apart by G Protein-Coupled Receptor Kinase 2

[Image: see text] The evolutionarily conserved DRY motif at the end of the third helix of rhodopsin-like, class-A G protein-coupled receptors (GPCRs) is a major regulator of receptor stability, signaling activity, and β-arrestin-mediated internalization. Substitution of the DRY arginine with histidi...

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Bibliografski detalji
Izdano u:Biochemistry
Glavni autori: Burczyk, Martina, Burkhalter, Martin D., Blätte, Tamara, Matysik, Sabrina, Caron, Marc G., Barak, Lawrence S., Philipp, Melanie
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2015
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310627/
https://ncbi.nlm.nih.gov/pubmed/25555130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501061h
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