Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor–related protein

The regulation of cerebrovascular permeability is critical for normal brain homeostasis, and the “breakdown” of the blood-brain barrier (BBB) is associated with the development of vasogenic edema and intracranial hypertension in a number of neurological disorders. In this study we demonstrate that a...

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Detalhes bibliográficos
Main Authors: Yepes, Manuel, Sandkvist, Maria, Moore, Elizabeth G., Bugge, Thomas H., Strickland, Dudley K., Lawrence, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC259131/
https://ncbi.nlm.nih.gov/pubmed/14617754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200319212
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