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The Low-Density Lipoprotein Receptor-Related Protein 1 Mediates Tissue-Type Plasminogen Activator-Induced Microglial Activation in the Ischemic Brain

Microglia are the immune cells of the central nervous system (CNS) that become activated in response to pathological situations such as cerebral ischemia. Tissue-type plasminogen activator (tPA) is a serine proteinase that is found in the intravascular space and the CNS. The low-density lipoprotein...

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Detalhes bibliográficos
Main Authors: Zhang, Chen, An, Jie, Strickland, Dudley K., Yepes, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630566/
https://ncbi.nlm.nih.gov/pubmed/19147818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080661
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