The Low-Density Lipoprotein Receptor-Related Protein 1 Mediates Tissue-Type Plasminogen Activator-Induced Microglial Activation in the Ischemic Brain

Microglia are the immune cells of the central nervous system (CNS) that become activated in response to pathological situations such as cerebral ischemia. Tissue-type plasminogen activator (tPA) is a serine proteinase that is found in the intravascular space and the CNS. The low-density lipoprotein...

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Bibliografiske detaljer
Main Authors: Zhang, Chen, An, Jie, Strickland, Dudley K., Yepes, Manuel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2009
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630566/
https://ncbi.nlm.nih.gov/pubmed/19147818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080661
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