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Regulation of seizure spreading by neuroserpin and tissue-type plasminogen activator is plasminogen-independent
Tissue-type plasminogen activator (tPA) is a highly specific serine proteinase expressed in the CNS during events that require neuronal plasticity. In this study we demonstrate that endogenous tPA mediates the progression of kainic acid–induced (KA-induced) seizures by promoting the synchronization...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151009/ https://ncbi.nlm.nih.gov/pubmed/12070304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14308 |
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