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X-Ray Crystal Structure of Mycobacterium Tuberculosis β-Ketoacyl Acyl Carrier Protein Synthase II (mtKasB)

Mycolic acids are long chain α-alkyl branched, β-hydroxy fatty acids that represent a characteristic component of the Mycobacterium tuberculosis cell wall. Through their covalent attachment to peptidoglycan via an arabinogalactan polysaccharide, they provide the basis for an essential outer envelope...

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Autors principals: Sridharan, Sudharsan, Wang, Lei, Brown, Alistair K., Dover, Lynn G., Kremer, Laurent, Besra, Gurdyal S., Sacchettini, James C.
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590929/
https://ncbi.nlm.nih.gov/pubmed/17174327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.11.006
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