Conformational transition of Sec machinery inferred from bacterial SecYE structures

Over 30% of proteins are secreted across or integrated into membranes. Their newly synthesized forms contain either cleavable signal sequences or non-cleavable membrane anchor sequences, which direct them to the evolutionarily conserved Sec translocon (SecYEG in prokaryotes and Sec61, comprising α-,...

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Bibliografiske detaljer
Main Authors: Tsukazaki, Tomoya, Mori, Hiroyuki, Fukai, Shuya, Ishitani, Ryuichiro, Mori, Takaharu, Dohmae, Naoshi, Perederina, Anna, Sugita, Yuji, Vassylyev, Dmitry G., Ito, Koreaki, Nureki, Osamu
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590585/
https://ncbi.nlm.nih.gov/pubmed/18923527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07421
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