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Conformational transition of Sec machinery inferred from bacterial SecYE structures
Over 30% of proteins are secreted across or integrated into membranes. Their newly synthesized forms contain either cleavable signal sequences or non-cleavable membrane anchor sequences, which direct them to the evolutionarily conserved Sec translocon (SecYEG in prokaryotes and Sec61, comprising α-,...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2590585/ https://ncbi.nlm.nih.gov/pubmed/18923527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07421 |
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