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Neutral evolution in paroxysmal nocturnal hemoglobinuria
Paroxysmal nocturnal hemoglobinuria is an acquired hematopoietic stem cell (HSC) disorder characterized by the partial or complete deficiency of glycosyl-phosphatidylinositol (GPI)-linked membrane proteins, which leads to intravascular hemolysis. A loss of function mutation in the PIG-A gene, requir...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587638/ https://ncbi.nlm.nih.gov/pubmed/19011109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802749105 |
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