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Neutral evolution in paroxysmal nocturnal hemoglobinuria

Paroxysmal nocturnal hemoglobinuria is an acquired hematopoietic stem cell (HSC) disorder characterized by the partial or complete deficiency of glycosyl-phosphatidylinositol (GPI)-linked membrane proteins, which leads to intravascular hemolysis. A loss of function mutation in the PIG-A gene, requir...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dingli, David, Luzzatto, Lucio, Pacheco, Jorge M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587638/
https://ncbi.nlm.nih.gov/pubmed/19011109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802749105
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