Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease

Dopaminergic cell death in the substantia nigra (SN) is central to Parkinson's disease (PD), but the neurodegenerative mechanisms have not been completely elucidated. Iron accumulation in dopaminergic and glial cells in the SN of PD patients may contribute to the generation of oxidative stress,...

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Main Authors: Salazar, Julio, Mena, Natalia, Hunot, Stephane, Prigent, Annick, Alvarez-Fischer, Daniel, Arredondo, Miguel, Duyckaerts, Charles, Sazdovitch, Veronique, Zhao, Lin, Garrick, Laura M., Nuñez, Marco T., Garrick, Michael D., Raisman-Vozari, Rita, Hirsch, Etienne C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587621/
https://ncbi.nlm.nih.gov/pubmed/19011085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804373105
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