Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease

Dopaminergic cell death in the substantia nigra (SN) is central to Parkinson's disease (PD), but the neurodegenerative mechanisms have not been completely elucidated. Iron accumulation in dopaminergic and glial cells in the SN of PD patients may contribute to the generation of oxidative stress,...

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Detalhes bibliográficos
Main Authors: Salazar, Julio, Mena, Natalia, Hunot, Stephane, Prigent, Annick, Alvarez-Fischer, Daniel, Arredondo, Miguel, Duyckaerts, Charles, Sazdovitch, Veronique, Zhao, Lin, Garrick, Laura M., Nuñez, Marco T., Garrick, Michael D., Raisman-Vozari, Rita, Hirsch, Etienne C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587621/
https://ncbi.nlm.nih.gov/pubmed/19011085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804373105
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