Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin

The Gram-negative bacterium Vibrio cholerae is the causative agent of a severe diarrheal disease that afflicts three to five million persons annually, causing up to 200,000 deaths. Nearly all V. cholerae strains produce a large multifunctional-autoprocessing RTX toxin (MARTX(Vc)), which contributes...

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Bibliografske podrobnosti
Main Authors: Kudryashov, Dmitri S., Durer, Zeynep A. Oztug, Ytterberg, A. Jimmy, Sawaya, Michael R., Pashkov, Inna, Prochazkova, Katerina, Yeates, Todd O., Loo, Rachel R. Ogorzalek, Loo, Joseph A., Satchell, Karla J. Fullner, Reisler, Emil
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587553/
https://ncbi.nlm.nih.gov/pubmed/19015515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808082105
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