Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin

The Gram-negative bacterium Vibrio cholerae is the causative agent of a severe diarrheal disease that afflicts three to five million persons annually, causing up to 200,000 deaths. Nearly all V. cholerae strains produce a large multifunctional-autoprocessing RTX toxin (MARTX(Vc)), which contributes...

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Main Authors: Kudryashov, Dmitri S., Durer, Zeynep A. Oztug, Ytterberg, A. Jimmy, Sawaya, Michael R., Pashkov, Inna, Prochazkova, Katerina, Yeates, Todd O., Loo, Rachel R. Ogorzalek, Loo, Joseph A., Satchell, Karla J. Fullner, Reisler, Emil
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2008
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587553/
https://ncbi.nlm.nih.gov/pubmed/19015515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808082105
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