Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin

The Gram-negative bacterium Vibrio cholerae is the causative agent of a severe diarrheal disease that afflicts three to five million persons annually, causing up to 200,000 deaths. Nearly all V. cholerae strains produce a large multifunctional-autoprocessing RTX toxin (MARTX(Vc)), which contributes...

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Detalhes bibliográficos
Main Authors: Kudryashov, Dmitri S., Durer, Zeynep A. Oztug, Ytterberg, A. Jimmy, Sawaya, Michael R., Pashkov, Inna, Prochazkova, Katerina, Yeates, Todd O., Loo, Rachel R. Ogorzalek, Loo, Joseph A., Satchell, Karla J. Fullner, Reisler, Emil
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587553/
https://ncbi.nlm.nih.gov/pubmed/19015515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808082105
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