F-actin structure destabilization and DNase-I binding loop fluctuations: MUTATIONAL CROSS-LINKING AND ELECTRON MICROSCOPY ANALYSIS OF THE LOOP STATES AND EFFECTS ON F-ACTIN

The conformational dynamics of filamentous actin (F-actin) is essential for the regulation and functions of cellular actin networks. The main contribution to F-actin dynamics and its multiple conformational states arises from the mobility and flexibility of the DNase-I binding loop (D-loop, residues...

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Detalhes bibliográficos
Main Authors: Durer, Zeynep A. Oztug, Diraviyam, Karthikeyan, Sept, David, Kudryashov, Dmitri S., Reisler, Emil
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070609/
https://ncbi.nlm.nih.gov/pubmed/19900461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.11.001
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