Morphine-induced μ-Opioid Receptor Rapid Desensitization is independent of Receptor Phosphorylation and β-Arrestins

Receptor desensitization involving receptor phosphorylation and subsequent βArrestin (βArr) recruitment has been implicated in the tolerance development mediated by μ-opioid receptor (OPRM1). However, the roles of receptor phosphorylation and βArr on morphine-induced OPRM1 desensitization remain to...

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Detaylı Bibliyografya
Asıl Yazarlar: Chu, Ji, Zheng, Hui, Loh, Horace H., Law, Ping-Yee
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587504/
https://ncbi.nlm.nih.gov/pubmed/18558479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2008.05.004
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