Loading...
Synthesis, Ex Vivo Evaluation and Radiolabeling of Potent 1,5-Diphenyl-pyrrolidin-2-one Cannabinoid Subtype-1 (CB(1)) Receptor Ligands as Candidates for In Vivo Imaging
We have reported that [methyl-(11)C](3R,5R)-5-(3-methoxy-phenyl)-3-((R)-1-phenyl-ethylamino)-1-(4-trifluoromethyl-phenyl)-pyrrolidin-2-one ([(11)C]8, [(11)C]MePPEP) binds with high selectivity to cannabinoid type-1 (CB(1)) receptors in monkey brain in vivo. We now describe the synthesis of 8 and fou...
Na minha lista:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587418/ https://ncbi.nlm.nih.gov/pubmed/18800770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800416m |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|