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Total Synthesis of (–)- and ent-(+)-Vindoline
Two exceptionally concise total syntheses of (–)- and ent-(+)-vindoline are detailed enlisting a diastereoselective tandem [4+2]/[3+2] cycloaddition of a 1,3,4-oxadiazole. The unique reaction cascade assembles the fully functionalized pentacyclic ring system of vindoline in a single step that forms...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587129/ https://ncbi.nlm.nih.gov/pubmed/16178578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol051975x |
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