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Increased TLR responses in dendritic cells lacking the ITAM-containing adapters DAP12 and FcRγ
The inhibitory effect of DAP12 on macrophages has been revealed by examining myeloid cells from DAP12-deficient mice. In this report, we demonstrate that both DAP12 and the FcεRIγ-chain (FcRγ) are required for negative regulation of TLR responses in bone marrow-derived dendritic cells (DC). Loss of...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587008/ https://ncbi.nlm.nih.gov/pubmed/18081038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737600 |
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