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Increased TLR responses in dendritic cells lacking the ITAM-containing adapters DAP12 and FcRγ

The inhibitory effect of DAP12 on macrophages has been revealed by examining myeloid cells from DAP12-deficient mice. In this report, we demonstrate that both DAP12 and the FcεRIγ-chain (FcRγ) are required for negative regulation of TLR responses in bone marrow-derived dendritic cells (DC). Loss of...

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書誌詳細
主要な著者: Chu, Ching-Liang, Yu, Yen-Ling, Shen, Kuan-Yin, Lowell, Clifford A., Lanier, Lewis L., Hamerman, Jessica A.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587008/
https://ncbi.nlm.nih.gov/pubmed/18081038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737600
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