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Opposite Effects of Zinc on Human and Rat P2X(2) Receptors
P2X(2) receptors from rats show potentiation when a submaximal concentration of ATP is combined with zinc in the range of 10–100 μm. Alignment of the amino acid sequences of human P2X(2) (hP2X(2)) and rat P2X(2) (rP2X(2)) indicated that only one of two histidines essential for zinc potentiation in r...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586956/ https://ncbi.nlm.nih.gov/pubmed/18971456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2763-08.2008 |
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