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The role of histidine residues in modulation of the rat P2X(2) purinoceptor by zinc and pH

P2X(2) receptor currents are potentiated by acidic pH and zinc. To identify residues necessary for proton and zinc modulation, alanines were singly substituted for each of the nine histidines in the extracellular domain of the rat P2X(2) receptor. Wild-type and mutant receptors were expressed in Xen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Clyne, J Dylan, LaPointe, Lisa D, Hume, Richard I
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Science Inc 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290168/
https://ncbi.nlm.nih.gov/pubmed/11882669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.013244
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