Full sensitivity of P2X2 purinoceptor to ATP revealed by changing extracellular pH.

A full pharmacological characterization was carried out on a recombinant ATP-gated ion channel (P2X2 purinoceptor) expressed in Xenopus oocytes. This slowly-desensitizing neuronal P2X2 purinoceptor, activated by ATP (EC50 = 4.6 +/- 1 microM at pH 7.4; n = 4), showed the agonist potency order: ATP &g...

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Bibliographic Details
Main Authors: King, B. F., Ziganshina, L. E., Pintor, J., Burnstock, G.
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909447/
https://ncbi.nlm.nih.gov/pubmed/8730726
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