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Modulation of ATP-responses at recombinant rP2X(4) receptors by extracellular pH and zinc

1. The modulatory effects of extracellular H(+) and Zn(2+) were tested against ATP-responses at rat P2X(4) (rP2X(4)) receptors expressed in Xenopus oocytes under voltage-clamp conditions. 2. ATP (0.1–100 μM, at pH 7.5), evoked inward currents via rP2X(4) receptors (EC(50) value, 4.1±0.98 μM; n(H), 1...

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Detalhes bibliográficos
Main Authors: Wildman, S S, King, B F, Burnstock, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565836/
https://ncbi.nlm.nih.gov/pubmed/10188989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702325
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