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Opposite Effects of Zinc on Human and Rat P2X(2) Receptors

P2X(2) receptors from rats show potentiation when a submaximal concentration of ATP is combined with zinc in the range of 10–100 μm. Alignment of the amino acid sequences of human P2X(2) (hP2X(2)) and rat P2X(2) (rP2X(2)) indicated that only one of two histidines essential for zinc potentiation in r...

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Detalhes bibliográficos
Main Authors: Tittle, Rachel K., Hume, Richard I.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586956/
https://ncbi.nlm.nih.gov/pubmed/18971456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2763-08.2008
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