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Genetic Interaction Between NRAS and BRAF Mutations and PTEN/MMAC1 Inactivation in Melanoma

Extant evidence implicates growth factor signaling in the pathogenesis of many tumor types, including cutaneous melanoma. Recently, reciprocal activating mutations of NRAS and BRAF were found in benign melanocytic nevi and cutaneous melanomas. We had previously reported a similar epistatic relations...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tsao, Hensin, Goel, Vikas, Wu, Heng, Yang, Guang, Haluska, Frank G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586668/
https://ncbi.nlm.nih.gov/pubmed/15009714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0022-202X.2004.22243.x
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