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NRAS and BRAF Mutations in Melanoma-Associated Nevi and Uninvolved Nevi

According to the prevailing multistep model of melanoma development, oncogenic BRAF or NRAS mutations are crucial initial events in melanoma development. It is not known whether melanocytic nevi that are found in association with a melanoma are more likely to carry BRAF or NRAS mutations than uninvo...

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Detalhes bibliográficos
Main Authors: Tschandl, Philipp, Berghoff, Anna Sophie, Preusser, Matthias, Burgstaller-Muehlbacher, Sebastian, Pehamberger, Hubert, Okamoto, Ichiro, Kittler, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704624/
https://ncbi.nlm.nih.gov/pubmed/23861977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069639
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