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NRAS and BRAF Mutations in Melanoma-Associated Nevi and Uninvolved Nevi

According to the prevailing multistep model of melanoma development, oncogenic BRAF or NRAS mutations are crucial initial events in melanoma development. It is not known whether melanocytic nevi that are found in association with a melanoma are more likely to carry BRAF or NRAS mutations than uninvo...

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Hlavní autoři: Tschandl, Philipp, Berghoff, Anna Sophie, Preusser, Matthias, Burgstaller-Muehlbacher, Sebastian, Pehamberger, Hubert, Okamoto, Ichiro, Kittler, Harald
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704624/
https://ncbi.nlm.nih.gov/pubmed/23861977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069639
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