TIMP-3 Suppresses Tumor Angiogenesis in MMP-2-downregulated Lung Cancer

Matrix metalloproteinase-2 (MMP-2) expression is often upregulated in advanced cancers and known to play important role in tumor angiogenesis. We previously showed that adenoviral-mediated delivery of siRNA for MMP-2 (Ad-MMP-2-Si) inhibited lung cancer growth, angiogenesis and metastasis. In this st...

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Detalhes bibliográficos
Main Authors: Chetty, Chandramu, Lakka, Sajani S., Praveen, Bhoopathi, Kunigal, Sateesh, Geiss, Roger, Rao, Jasti S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586602/
https://ncbi.nlm.nih.gov/pubmed/18559520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6612
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