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All-Atom Computer Simulations of Amyloid Fibrils Disaggregation

Amyloidlike fibrils are found in many fatal diseases, including Alzheimer's disease, type II diabetes mellitus, transmissible spongiform encephalopathies, and prion diseases. These diseases are linked to proteins that have partially unfolded, misfolded, and aggregated into amyloidlike fibrils....

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Detalhes bibliográficos
Main Authors: Wang, Jun, Tan, Chunhu, Chen, Hai-Feng, Luo, Ray
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586582/
https://ncbi.nlm.nih.gov/pubmed/18757563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.131672
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